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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TLR2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID7097
Official gene symbolTLR2
Full nametoll-like receptor 2
Aliases,CD282,TIL4,
Gene summaryThe protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB. [provided by RefSeq]
LocationChromosome: 4   Locus: 4q32
Gene position154605441 - 154627243  Map Viewer
Gene orientationplus
Gene size21803 bp
Gene sequence
OMIM ID603028