Entrez gene ID | | 7128 |
Official gene symbol | | TNFAIP3 |
Full name | | tumor necrosis factor, alpha-induced protein 3 |
Aliases | | ,A20,MGC104522,MGC138687,MGC138688,OTUD7C,TNFA1P2, |
Gene summary | | This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. Knockout studies of a similar gene in mice suggested that this gene is critical for limiting inflammation by terminating TNF-induced NF-kappa B responses. [provided by RefSeq] |
Location | | Chromosome: 6 Locus: 6q23 |
Gene position | | 138188581 - 138204449 Map Viewer |
Gene orientation | | plus |
Gene size | | 15869 bp |
Gene sequence |
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OMIM ID | | 191163 |