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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TNNI3 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 7137 Official gene symbol TNNI3 Full name troponin I type 3 (cardiac) Aliases ,CMD1FF,CMD2A,CMH7,MGC116817,RCM1,TNNC1,cTnI, Gene summary Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq] Location Chromosome: 19   Locus: 19q13.4 Gene position 55669100 - 55663135  Map Viewer Gene orientation minus Gene size 5966 bp Gene sequence >TNNI3:complement(27931353..27937318):Length=5966 AGTGTCCTCGGGGAGTCTCAAGCAGCCCGGAGGAGACTGACGGTCCCTGGGACCCTGAAG GTCACCCGGGCGGCCCCCTCACTGACCCTCCAAACGCCCCTGTCCTCGCCCTGCCTCCTG CCATTCCCGGCCTGAGTCTCAGCATGGCGGATGGGTGAGTGATGCCCCAAGGCAGTGGGA GTTGGGGGCGACCTCCCGGGTTCCCAAGAGGGGTCGCAGCTGAGAGGCTGGACCCTTGGC CTGCGAGGTAGGCGTAGGGACTCTTGGGTGAAGAGAGGAAGTGGGTTTGCGAGTCAGACT CCTGGAACCCAAGGAAGGGGAAGCGCGGTCCCCCGACCTCTTGTTCAGAGGGGACTCCAG GGGTCCCTTAGGAGACAGGACACAGCCCACCACTAACCCCCCTCCTTGGTTTCTCTCCTT CCAGGAGCAGCGATGCGGTGAGAGCAGCGGGCTAAGGCGTGGCTGGGACCCCCAGGGCCA GGGTGGGCGCTGCAGTGAGGGGTCTGGGGCGGGAGGCTGCAGCCCTAGCAGAGGGTGCGG TACGGTAAGGGCTGGGTGGGGTCTTGGTGGTGATGGGGTCCCCACTCCTCCTAACCCAGG CTAGGGAACCTCGCCCTGCACCAGCCCCAATCAGACGCCGCTCCTCCAACTACCGCGCTT ATGCCACGGAGCCGCACGCCAAGGTGGGACGGGGCTTCCTGGGGGCAGAGTACAGGCGCC GGAGGGATCCAAGACCCTGGGAGTGGGGGGAGGAGCCAGGGCTGCGAAGGGGGCGGGGAC TACGCGGAGGGGCTTCAGGGGCGGAGTTTTGCAGAGGGTCATGCTCGGATTGGTGACAGC AGCCTGCGGGCGGAACTCCGTTGCCCTCGGACTTGCTTAGGGATAGATGGGAAGTGCCTA TCCAAAGGAAGAGACCCAGATTGGTGGATGGGAATGAGGGGCGTGGCCTCCCGTAGACTC AGGGCTCAAGTTGGACGTGGGCCCAAATCTGGACCGGCTGGGTTTGCTGGGGGTGTCTTG AGGTCCCCTCCACCGTCGTCTCCGAATCCCCCTCCATGATCCTTCCTTGCTCCATCTCAC CCTGGCAGAAAAAATCTAAGATCTCCGCCTCGAGAAAATTGCAGCTGAAGGTGAGGACGG GCGGGACTGGGAAAGAGCAGGCAGGTGCTCAGGGGGCGGAGCTTGAGAATGGGTGGGGCT TTCGGGGTAGGTGGGCGGAAGTGGGCGGGGTTTGGCCGCTCGGGGCGTGGCTTTAGCGGG GAGTACTGCTCGGGGTGGGACGGGGCCTTGGAACAGTGGAGACCAAACTGGAGGGTTTAG AAGGGCAGAGGCGGTTCCCCACGCCTGGTCTTTATCCTGAAGCCCCGGGTGGGCTGCGCT TCCCTCCCACCCCTCTGCAGACTCTGCTGCTGCAGATTGCAAAGCAAGAGCTGGAGCGAG AGGCGGAGGAGCGGCGCGGAGAGAAGGGGCGCGCTCTGAGCACCCGCTGCCAGCCGCTGG AGTTGGCCGGGCTGGGCTTCGCGGAGCTGCAGGTACCGGCTCCCAAGGATGCGAGGTTTC TAGTCCCGGAATTCAGCAGTACAGCCTCTATCCCCTCTTCTGCTCGGGACCCAGGCGTCC AATATGGCTGTCCTTACCCAATTATATATGGTTCGTGGGACTCCTGGCCCCTAACACCCT TTGTGTGCAGGTCTGTGGAGTCTTGGCTCCAACCTACTCCTTCAGGACCATGTGGCCCTC CTATCCCAGACAGAAGCCCAAGCCCCAGCCCCTCCTCCCTCAGACCCTGGAGTCCAGGCC CCAGCCCCTCCTCCCTCAGACCCAGGAGTCCAGTCCCCAGCCCCTCCTCCCTGAGACCCT GAAGTCCAGGCCCCAGCCCCTCCTCCCTCAGACCCTGGAGTCCAGGCCCCAGCCCCTCCT CCCTCAGACCCTGGAGTCCAGGCCCCAGCCCCTCCTCCCTCAGACCCTGGAGTCCAGGCC CCCAGCCCCTCCTCCCTCAGACCCTGGAGTCCAGGCCCCAGCCCCTCCTCCCTCAGACCC AGGAGTCCAGTCCCCAGCCCCTCCTCCCTCAGACCCTGGAATCGAGGCCCTCAGCCCCTC CTCCCTCAGACCCTGAAGTCCAGGCCCCAGCCCCTCCTCCCTCAGACCCTGAAGTCCAGG CCCCAGCCCCTCCTCCCTCAGACCCTGAAGTCCAGGCCCCAGCCCCTCCTCCCTCAGACC CAGGAGTCCAGTCCCCAGCCCCTCCTCCCTCAGACCCTGGAGTCCAGGCCCCAGCCCCTC CTCCCTCAGACCCTGGAGTCCAGGCCCCAGCCTCTCCTCCCTGAGACCCTGGAGTCCAGG CCCCAGCCTCTCCTCCCTCAGACCCTGGAGTCCAGGCCCCAGCCCCTCCTCCCTCAGACC CTGGAGTCCAGGCCCCAGCTCCTCCTCCCTCAGACCCTGGAGTCCAGGCCCCAGCCCCTC CTCCCTCAGACCCTGGAGTCCAGGCCCCAGCCCCTCCTCCCTCAGACCCAGGAGTCCAGT CCCCAGCCCCTCCTCCCTCAGACCCTGAAGTCCAGGCCCCAGCCCCTCCTCCCTCAGACC CAGGAGTCCAGTCCCCAGCCCCTCCTCCCTCAGACCCAGGAGTCCAGTCCCCAGCCCCTC CTCCCTCAGACCCTGGAATCGAGGCCCTCAGCCCCTCCTCCCTCAGACCCAGGAGTCCAG GCCCCCAGCCCCTTCTCCTCCCTCAAACCCAGGAGTCCAGGCCCCCAACTCCTCCCTCAG ACCCAGGAGTCCAGGCCCCCAGCCCCTTCTCCTCCCTCAGACCCAGGAGTCCAGGCCCCG AGCCCCTTCTCCCTCAGACCCAGGAGTCCAGGTCTCCCTGTTTTTGGTTCCCCCAACAAC ACACACCACGTTCCTCCTCCAGGACTTGTGCCGACAGCTCCACGCCCGTGTGGACAAGGT GGATGAAGAGAGATACGACATAGAGGCAAAAGTCACCAAGAACATCACGGAGGTGGGACG CATGGGCAGCTCGGGTACCTTCGGGGTAGGGTGAGATGGCTGGGACTTGGTCTCTGCCTG ACCCCTTGCAGCTGCTTTTGGCTGCACATCCCAGGAGACCCAGGACAACTGTGAGCCTGG CAGGGCTGGGGCAGAAGGATGAGTACAATATAGTCAAGGAAAGCTGTTCTAGGCAGAGGG AACAGCACATGCAAGGCCATGGGTTGGGAAACAGAAAATAAGTTAGTGAACATGCTCAGG GCATCACATGTTGGTAAATTAGCTCAGGCACTGGCCAGGGAATTGTGATTTGCATGTAGC TGGACCAGGTTATGCCAGTGGTTTTGAGAGGTGAGGCTGGAGCATATGAGGAGGGGGATT CAGTTCCAGGATTAGAAGCCTAGACTGGGAGCCTAAGCCGGGAAGAGACTGGTAAGGCCT CGGTACTGGAAGACGAGATAAGGAGAATAAAAAAGGAGTGTAGGATGGAGGAGTTGGGTG TGCGGGAAATGGAAGGAGAAGTACCCACCCCCTCGTTTGCCCCCAGATTGCAGATCTGAC TCAGAAGATCTTTGACCTTCGAGGCAAGTTTAAGCGGCCCACCCTGCGGAGAGTGAGGAT CTCTGCAGATGCCATGATGCAGGCGCTGCTGGGGGCCCGGGCTAAGGAGTCCCTGGACCT GCGGGCCCACCTCAAGCAGGTGAAGAAGGAGGACACCGAGAAGGTGAGTGTGGGCTAAGG CCAGGAAAGAGGATGCTGAGGGGAAGGGCTGTGGGTGCCAACAACCCTAGGCCTGAGGGC AGATGGTGCTTGGAGTTGGAGGTAGAAGCAGCTAGTAAGGGGTCCTCAGAAATGCAAGAG GAAGACAGGAAGTAGAAGGGGAAGACAGGAAGTGCATTAGGGCTACAGGAAGTCCATGTA AGAGCAAAGAGGTACATGAAGGTCCAGGTGCAGTGGCTTATGCCTGTAATCTTTGAGGTT TAAAAAAAATTTTTTTTTAATTTCCTTTTTTTTTTTTTTTTGCGATGGAGTCTCTGCTGC CCAGGCTGGAGTGCAATGACACCATCTCGGTTGCTGGAGTGCAGTGACACCATCTCGGCT CACTGCAACCTCTGCCTCCCAGGATCAAGTGATTCTCATGCCTCAGCCTCCCGAGTAGCT GGGACTACAGGTGCACACCACCATGTTGTTGTTTTAATTTCTACAAATTTCTTTTTTAAA TTAGCCAGTCACGGTGGTGGCATGCAGCTTCTCAGGAGGCTGAGGCAGGAAAATCGCTTG AGCCCATGAGATCGAGGGTGCAGTGAGCTATGACTGCACCACTGCACTCCAGCCTGGGCA ATACAGTGAGACCCTATCTTAAAGAAGAAGACAGGAAAGATAGGAGTGGATGCCTGAAAC CATGGATTGTACTGAACCCTATATGTAATTTTTTTTCCTATACACACATACATACCTATG ATAAAGTTTCATTTCTAAATTAGACACAGTAAGAGATTAACAATAAATAACAACAAAAGA AGGTTGGGCGTGGTGGCTCATGCCTGTAATCTCAACACTTTGGGATGCTAAGGCAGGCAG ATTGCTTGAGCTCTGGAGTTCGAGACCAGCCTGGGCAACATGGCGAGACCATGTCTCTAT AAAAAATACCAAAGTTACCGGGTGTGGTGGCTCGTGCCTGTAATCCCAGCGCTTTGGGAG GCCAAGGCGGGCGGATCATGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACACAGTGAAA CCCCACCTGTAGTAAAAATACAAACATTTGCTGGGCGTGGTCGTGGGTGCCTGTAATCCC AGCTACTTGTGAAGCTGAGGCAGGAGAATTGCTTGAACCCGGGAGGCAGAGGTTGCAGTG AGCCGAGATCTCACCACTGCACTCCAGCCCAGGCAACACTGGGAGACTCCATCTCAAAAC AAAACAAAACAGAACAAAAGTTAGCTGGGCATGGTGGCACACACCTGTGGTCCCAGCTCC TCAGGAGTCTGAGGTGAGAGGATGGCTTGAGCCCAGGAAGTTGAGGCTGCAGTGAGCCGA GATTGCACGACTGCACTCCAGCTTGGATGAGGCAGCCAGACCCTGTCTCAAATAATAATA ATAATAAAATAGAACAATTATAACAGATTGTAATAAAACTCATGAATGTGGTCTCTTTCT CAAAATATCTTATAGCACTGTAATCACCCTTCTTTTCCTTGTGATGTAAAATGACAGTGC CTATGTGCTGAGATGAGGTGAGGTGGATGACATAGGCATTATGACCTGGCGTTAGGCTAC TATTGACCTGAGAATCCATCAAACTTATGAATTGTTTATTTCTGGAATTTTCCATTTAAT ATTTTTGGGCCATGGTTTACCTCAGGTAACTGAAACCACACAAAGTAAAATTGCAGAAAA GGAGGGACTACTATAATAAGAAGAGAAGGAAGGAGACAGGAAGGGCATAAGGCAGACAGG AAGTGGAGGGGAAAGATAGGAAGTGCAGGAAGGAGACAGGAAGTGGAGGGGAAAGACAGG AAGTGCATGAGGGAGACAGGAAGTGGATGGGGAAAGACAGAAAGTACATGAGGGAGACAG GAAGTGCTGGGGAAAGACAGGAAGTGCATGAGGGGGACAGGAAGTGCATGAGGGAGACAG GAAGTGCATGGGGAAAATTGGCAGGGATTATCTTGAAAAGACAGGAAGTGCTCCAGAACT AGATACTTAGGCATCCAGGGTAGAGTGGCCCCACAGGCTGGAGGGAAGACAGGGATTCTT GAGAGACTGGAGACCAAGAAGAGACCCTAACCTCTGACTCATCGCCATCCTCCAGGAAAA CCGGGAGGTGGGAGACTGGCGCAAGAACATCGATGCACTGAGTGGAATGGAGGGCCGCAA GAAAAAGTTTGAGAGCTGAGCCTTCCTGCCTACTGCCCCTGCCCTGAGGAGGGCCCTGAG GAATAAAGCTTCTCTCTGAGCTGAAA OMIM ID 191044