Entrez gene ID | | 7150 |
Official gene symbol | | TOP1 |
Full name | | topoisomerase (DNA) I |
Aliases | | ,TOPI, |
Gene summary | | This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22. [provided by RefSeq] |
Location | | Chromosome: 20 Locus: 20q12-q13.1 |
Gene position | | 39657462 - 39753127 Map Viewer |
Gene orientation | | plus |
Gene size | | 95666 bp |
Gene sequence |
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OMIM ID | | 126420 |
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