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Gene information for TOP1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID7150
Official gene symbolTOP1
Full nametopoisomerase (DNA) I
Aliases,TOPI,
Gene summaryThis gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22. [provided by RefSeq]
LocationChromosome: 20   Locus: 20q12-q13.1
Gene position39657462 - 39753127  Map Viewer
Gene orientationplus
Gene size95666 bp
Gene sequence
OMIM ID126420