Entrez gene ID | | 7161 |
Official gene symbol | | TP73 |
Full name | | tumor protein p73 |
Aliases | | ,P73, |
Gene summary | | This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, however, the biological validity and the full-length nature of most variants have not been determined. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1p36.3 |
Gene position | | 3569129 - 3650467 Map Viewer |
Gene orientation | | plus |
Gene size | | 81339 bp |
Gene sequence |
| |
OMIM ID | | 601990 |
|