Entrez gene ID | | 7166 |
Official gene symbol | | TPH1 |
Full name | | tryptophan hydroxylase 1 |
Aliases | | ,MGC119994,TPRH,TRPH, |
Gene summary | | This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others. |
Location | | Chromosome: 11 Locus: 11p15.3-p14 |
Gene position | | 18062335 - 18042084 Map Viewer |
Gene orientation | | minus |
Gene size | | 20252 bp |
Gene sequence |
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OMIM ID | | 191060 |
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