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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TPH1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID7166
Official gene symbolTPH1
Full nametryptophan hydroxylase 1
Aliases,MGC119994,TPRH,TRPH,
Gene summaryThis gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.
LocationChromosome: 11   Locus: 11p15.3-p14
Gene position18062335 - 18042084  Map Viewer
Gene orientationminus
Gene size20252 bp
Gene sequence
OMIM ID191060