Entrez gene ID | | 7247 |
Official gene symbol | | TSN |
Full name | | translin |
Aliases | | ,BCLF-1,RCHF1,REHF-1,TBRBP,TRSLN, |
Gene summary | | This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. [provided by RefSeq] |
Location | | Chromosome: 2 Locus: 2q21.1 |
Gene position | | 122513121 - 122525429 Map Viewer |
Gene orientation | | plus |
Gene size | | 12309 bp |
Gene sequence |
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OMIM ID | | 600575 |