Entrez gene ID | | 7264 |
Official gene symbol | | TSTA3 |
Full name | | tissue specific transplantation antigen P35B |
Aliases | | ,FX,P35B,SDR4E1, |
Gene summary | | Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II. [provided by RefSeq] |
Location | | Chromosome: 8 Locus: 8q24.3 |
Gene position | | 144699732 - 144694788 Map Viewer |
Gene orientation | | minus |
Gene size | | 4945 bp |
Gene sequence |
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OMIM ID | | 137020 |
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