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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TNFSF4 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID7292
Official gene symbolTNFSF4
Full nametumor necrosis factor (ligand) superfamily, member 4
Aliases,CD134L,CD252,GP34,OX-40L,OX4OL,TXGP1,
Gene summaryThe protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF4/OX4. It is found to be involved in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD40-stimulated B cells, this cytokine along with CD70 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells. [provided by RefSeq]
LocationChromosome: 1   Locus: 1q25
Gene position173176471 - 173152870  Map Viewer
Gene orientationminus
Gene size23602 bp
Gene sequence
OMIM ID603594