Entrez gene ID | | 7327 |
Official gene symbol | | UBE2G2 |
Full name | | ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast) |
Aliases | | ,UBC7, |
Gene summary | | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse counterpart. This gene is ubiquitously expressed, with high expression seen in adult muscle. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 21 Locus: 21q22.3 |
Gene position | | 46221738 - 46188955 Map Viewer |
Gene orientation | | minus |
Gene size | | 32784 bp |
Gene sequence |
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OMIM ID | | 603124 |
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