Entrez gene ID | | 7345 |
Official gene symbol | | UCHL1 |
Full name | | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
Aliases | | ,PARK5,PGP 9.5,PGP9.5,PGP95,Uch-L1, |
Gene summary | | The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease. |
Location | | Chromosome: 4 Locus: 4p14 |
Gene position | | 41258898 - 41270446 Map Viewer |
Gene orientation | | plus |
Gene size | | 11549 bp |
Gene sequence |
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OMIM ID | | 191342 |