Entrez gene ID | | 7348 |
Official gene symbol | | UPK1B |
Full name | | uroplakin 1B |
Aliases | | ,TSPAN20,UPIB,UPK1, |
Gene summary | | The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 3 Locus: 3q13.3-q21 |
Gene position | | 118892425 - 118924000 Map Viewer |
Gene orientation | | plus |
Gene size | | 31576 bp |
Gene sequence |
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OMIM ID | | 602380 |
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