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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for UPK1B (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID7348
Official gene symbolUPK1B
Full nameuroplakin 1B
Aliases,TSPAN20,UPIB,UPK1,
Gene summaryThe protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq]
LocationChromosome: 3   Locus: 3q13.3-q21
Gene position118892425 - 118924000  Map Viewer
Gene orientationplus
Gene size31576 bp
Gene sequence
OMIM ID602380