Entrez gene ID | | 7424 |
Official gene symbol | | VEGFC |
Full name | | vascular endothelial growth factor C |
Aliases | | ,Flt4-L,VRP, |
Gene summary | | The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D. [provided by RefSeq] |
Location | | Chromosome: 4 Locus: 4q34.1-q34.3 |
Gene position | | 177713895 - 177604691 Map Viewer |
Gene orientation | | minus |
Gene size | | 109205 bp |
Gene sequence |
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OMIM ID | | 601528 |
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