Entrez gene ID | | 7453 |
Official gene symbol | | WARS |
Full name | | tryptophanyl-tRNA synthetase |
Aliases | | ,GAMMA-2,IFI53,IFP53, |
Gene summary | | Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. Tryptophanyl-tRNA synthetase (WARS) catalyzes the aminoacylation of tRNA(trp) with tryptophan and is induced by interferon. Tryptophanyl-tRNA synthetase belongs to the class I tRNA synthetase family. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 14 Locus: 14q32.31 |
Gene position | | 100842680 - 100800125 Map Viewer |
Gene orientation | | minus |
Gene size | | 42556 bp |
Gene sequence |
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OMIM ID | | 191050 |
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