Entrez gene ID | | 7498 |
Official gene symbol | | XDH |
Full name | | xanthine dehydrogenase |
Aliases | | ,XO,XOR, |
Gene summary | | Xanthine dehydrogenase belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The enzyme is a homodimer. Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism. [provided by RefSeq] |
Location | | Chromosome: 2 Locus: 2p23.1 |
Gene position | | 31637611 - 31557188 Map Viewer |
Gene orientation | | minus |
Gene size | | 80424 bp |
Gene sequence |
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OMIM ID | | 607633 |
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