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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for XPC (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID7508
Official gene symbolXPC
Full namexeroderma pigmentosum, complementation group C
Aliases,RAD4,XP3,XPCC,
Gene summaryThis gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]
LocationChromosome: 3   Locus: 3p25
Gene position14220172 - 14186647  Map Viewer
Gene orientationminus
Gene size33526 bp
Gene sequence
OMIM ID613208