Entrez gene ID | | 7706 |
Official gene symbol | | TRIM25 |
Full name | | tripartite motif-containing 25 |
Aliases | | ,EFP,RNF147,Z147,ZNF147, |
Gene summary | | The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene. [provided by RefSeq] |
Location | | Chromosome: 17 Locus: 17q23.2 |
Gene position | | 54991409 - 54965270 Map Viewer |
Gene orientation | | minus |
Gene size | | 26140 bp |
Gene sequence |
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OMIM ID | | 600453 |
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