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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ZYX (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 7791 Official gene symbol ZYX Full name zyxin Aliases ,ESP-2,HED-2, Gene summary Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq] Location Chromosome: 7   Locus: 7q32 Gene position 143078360 - 143088204  Map Viewer Gene orientation plus Gene size 9845 bp Gene sequence >ZYX:3673983..3683827:Length=9845 CCCGCCCCCTCTCTTCTCCCTCCCTCCTCCTTCCGTGTGTCCCTCCCCGCCCGGCTGGAG GCTGCTCCGGACCGGGACGCAGAGTCTGCGGACCCGGCGCCGAGGCGGCCACCCGAGACG CGGCGCGCACGCTCCGGCCTGCGGTGAGGCGCGGGGAGCGGCAGGGCGGCCCCACGGGGA GGGGGCGCGGGGCGCCGGGAGGGGGCGAGTGGGGGTCACCAAGGGGAGCTGGGACCGCCT GGGGCTCCTGAGCCCGGCTCCGCGCTGCGTAACCCGGCGACCCACCCCAGCAGCCCGGCC CGGCCATGGCGGCCCCCCGCCCGTCTCCCGCGATCTCCGTTTCGGTCTCGGCTCCGGCTT TTTACGCCCCGCAGAAGAAGTTCGGCCCTGTGGTGGCCCCAAAGCCCAAAGTGAATCCCT TCCGGCCCGGGGACAGCGAGCCTCCCCCGGCACCCGGGGCCCAGCGCGCACAGATGGGCC GGGTGGGCGAGATTCCCCCGCCGCCCCCGGAAGGTATGCGGCGGGGCTTGGGGAATGTAC CCCGGCAGGAGCCGGGGTGGGGGGCAGTCGTTTCGGGAATTTGGGGATGTCTGGAAAGGT TGTTGCCGAGGGGGCTGGGCGCAGCCACCCTGTCCCGAGCAGATGTTCTTACCTCATCGT GGAGCTCGTGGCTGGGAGCCAGGGCTCCTGGGACCGTTCCAAGTCCCCCGCCTGGGAGTG GGAGTCGGGAATGTGGGGCACGAATCTTCCCCTCCGGGTCCGTTTTCCGAAGTGTAACGG GAGCTGCACCACTCCTCGGCAGTGCGCCCGGCCTTTCCTGACCTGGTACTCCCAGGGCGC CCTGCGCCCCTCCTTTGCTTCCCCACACGCTCTGGGACCCCTGAGAGAGTTCTTGGGTTA GGGGTTAGAGCGGTTAACTGAGGGGAGCTTGGGTGAGGGGTAGAGGGACCCCGGCCGACG TCTTTCTCCTTCCTACCCCAGACTTTCCCCTGCCTCCACCTCCCCTTGCTGGGGATGGCG ACGATGCAGAGGGTGCTCTGGGAGGTGCCTTCCCGCCGCCCCCTCCCCCGATCGAGGAAT CATTTCCCCCTGCGCCTCTGGAGGAGGAGATCTTCCCTTCCCCGCCGCCTCCTCCGGAGG AGGAGGGAGGGCCTGAGGCCCCCATACCGCCCCCACCACAGGTACGGAGGCCTGGGAGGG GCGGCTGCACTGGACACCCCCAAGGAGAGGAGAAGAGGGCCCTTTCTTCTTACCTCCCCT GCACCTCTGCCTTGGGGGTGGGGGGATAGAGGCATGGAATAGGTGCTCTGACCTCTGACC CTCTAGCCCAGGGAGAAGGTGAGCAGTATTGATTTGGAGATCGACTCTCTGTCCTCACTG CTGGATGACATGACCAAGAATGATCCTTTCAAAGCCCGGGTAAGGGACCGGAGAGTAGGA AAAGCAGGGCTCAGGGCCAGAGAGACTGGGCATAGAACTAAGGAGGATGGTGTCCTCCTG ACTGCATCTCTCTTCCCTCTCCCACCCCTTGCAGGTGTCATCTGGATATGTGCCCCCACC AGTGGCCACTCCATTCAGTTCCAAGTCCAGTACCAAGCCTGCAGCCGGGGGCACAGCACC CCTGCCTCCTTGGAAGTCCCCTTCCAGCTCCCAGCCTCTGCCCCAGGTTCCGGCTCCGGC TCAGAGCCAGACACAGTTCCATGTTCAGCCCCAGCCCCAGCCCAAGCCTCAGGTCCAACT CCATGTCCAGTCCCAGACCCAGCCTGTGTCTTTGGCTAACACCCAGCCCCGAGGGCCCCC AGCCTCATCTCCGGCTCCAGCCCCTAAGTTTTCTCCAGTGACTCCTAAGTTTACTCCTGT GGCTTCCAAGTTCAGTCCTGGAGCCCCAGGTGGATCTGGGTCACAACCAAATCAAAAATT GGGGCACCCCGAAGCTCTTTCTGCTGGCACAGGCTCCCCTCAACCTCCCAGCTTCACCTA TGCCCAGCAGAGGGAGAAGCCCCGAGTGCAGGAGAAGCAGCACCCCGTGCCCCCACCGGC TCAGAACCAAAACCAGGTGAGGGATGGTGATAGGACAAGGCTTGGTACCAGGGCACTGGG GCGGGGCTGGGTCAGGAGCCAGAGCATAAGCATAAGGTGATTGGAGAGTCAGGGTGGACA CGGGGGTTGCGGGGTGGCGGGATAGGAATTTTCATCCTCTGGGGTTAGCCTGGTGGAACA ATGGTAGGAAAATGCTCCTCTGGAGGAGAGGCCTGGCTGGGTGTGGGGCTGGGTGGGGCC TGGCTGGGACGGCGCAGAGAGCATGGGCTCTGAATTAGGAGGATCTGGTGGACCTTTCCT TGTGCCTTTACCCCAGAAAGTTAAAGGGAGGGATGAGATCACCAGTTCCACCTTGGTTTT TCCCATTCTTGGGTCTTGAGTTAATCTCCCTGCTCCTCTGAGCACTCTTTCTGCCTGAGG GCTTGGAGGTAAGAGACAGCCCCAGTAAACACTGGTTGAGCCAGCATCCACCACGTGCCA GGCACTGTGCTCTGTGCCCAGGAGGGTAGGACATGGGAGGGAAGAGATCTCTGCAAGAAG CTCAGCCTTCAGGTGTCAGATGGACCTGGAATGGAATTCTTGGCTCAGCTTCTCCCAAGT CCTTAGACTGGGCAAGTTAGGTGAACCCTGAGCCTCAGTTTCTCAATCTTTAACATTCTC TACTCCATACAGTGGTTGTGAAGATTGGGTGAGCTAATACCTAGAGAGTGTTGGGTTCTG TATCTAGTACAGGAATGCTCAAAATAGAAAAGCTGTAATTACAAAATGGTTCTTGCCTTC TAGTTCAGGAAATAAGATCGTCCAATTTCTGGTGACGAAGATGACCCTGATGGTCATCTA GTCCAAGCATCCAGAGTCCACTGATAGTGTTGATGTCTACCTACACTCGGACACAGCATA GGAAGAAATGCCAAGGGCCAGTGAGCTTTGCAGAATCCTGTGAGTCACAGGCACTCAGAC CAGGGAGTCAACTCGGGGAGTCAAATTAGGAAAGGCTTCGAAGGATGGGCAGGACGTAAG AATCCAGAGAGGAGAGGGATGTTTGGAGAACAGAAAGTGGAAGGTTCCTGTAGGAAAATG ATAGAGCTATACTTGGAGAGGCAAGCGGGGCTGGAGGGTGTAGGAGGTGAAGTGGCTCAC CCAAGGAGCTCTTGAGCACTGGAGAGGCATTCATGATTTTTGAGTAGGTGTGGGGTGGGT CAGGAGGGCTGGTGAAAGCAGTGTTTTTGGAAGCTTTCTGGAAAGTTTCACCAGCAGAGA TGTGTATTCGAGGGAGGTCAGTGATGGGTGTGAATTCACTCTTGGGCAATAGTAATGTTA GCTGCAATGAAAATTAAACCGTGCATGTGAGAGCTGTGTGCTAGAGCTGTTGGGAAGGCA CAGCCTCCAGGACTTAGCAAGGGATGAGCAATTGGAAGACAAGGGTGAGGGGAAGAGGGA AAAAAAAGTCTCCAGCACGATTTGGAGATGGGGTGTGGGCGGATGGCAGGATTGCTGACA AAATAGAGAAGTCCAGAAGGGGAAATGGTTTGGACGGGAAGAGGAGGGGTCCAGCTGTCA ACGTTTTGAGCAACAGGTCCCAGGAGGACTTTCAGCTGGGGCCGTCATTCAGCTAGAAAT CCAGGGCTAGGTTTCAGGAGAGGGCCAGAGATGTCTAGCATGGTAGTGGGGCACAGTGAC ACTGTGACGCTGGAGGGTCAGGGTCGGAGCGGAGGAGCTTCCCAGGGAGTGCAGACAGCG GGGACCAGGAGGTGCGGGAAGAAGAGTCAGGAGGAGAGTCAGGGTGCACTTGGAGAAGAG AGCTGAGCTCCTCAGTGGGGTATTTGAGGGAGTGAGGACTCAAGGCTAGAGATTAGACTG TTGGGAAATCATCAGCGGTCTTGGGATGGCCTGTTTGTGCCCTGTGGTGGGAACACAATG TGAGGAGTTGAGGAGAGAGTGGGTGGTGAGAAGTGGGGCTGCTGGTGTAGCCTGGTCTTA AAGGACTAAGGGAAGGACTGTGTGTCAGTGGTGTGTGTGTGTGTATATATACACATATGT GAATATATGAGTGGCGTGTGTGTGTGTGTTAGTGTGTGGGTGTGGGTATGGTGTATGTGA GTGTATGTGCATGTGTGAGCATGAATGTATGAGTGGCGTGTGATGTGTGTAGTGTGATTG TGTGAAAGTATGTGTATATGAGTACATGTGTGCATGTGTGAGTGAAGGTGTGTGCATGTG TGAGTGTGGCTGTGATGTGTATGGTGTGTGATTGCACAAGTGAAGGTGCACATACATACT TTCTTACAAATACACACAAGTGGCGTATGTGTATATATGTGAGTGGTGTGTGTGAGCGTG TGGTGTGGTATATCTTTTTTTTTTTTTTTTTTTTTTTTTTGGAGACGGAGTGCAGGCTGT CGCCCATGCTTACTACAACCTCCGCCCCCCTGGCTCAAACGATTCTCCTGTCTCAGCCTC CCAAGTAGCTGGGATTACAGGCACGTTCCACCACACCTGGCTAATTTTTGTATTTTTTAG TAGAGATGGGGTTTCACCATGTTGGCTAGGCTGGTCTCGAACTCCTGACCTCAAGTGATC TGCCTGCCTCAGCCTCCCAAAGTGTTGGGATTACAGGTGTGAGCCACCGCGCCTGGCCTG GTGTGGTATTATCTGAATGTGAGTGGTGTGTGTGTGTGTGGTATGGTATATGTGTGAGTG TGTGTGTGTGGTGTGGTATATGTGTGAGTGTATGTGAGTGGTGTATGTGTGTGGTCTGGT ATGTGTGTGTGCATGTGAGTGGTATGTGGGTATGTGTGAGGGTGTGTGTGTTTGAGTCTG TGGTGTAGCATATGTGGTTTTTGCAAGTTAGGGGAGAAGGGCTCAGGTACGTGTGTAACC CGGGGAAGCAGGTGATGGAGGGTGAGTGTTGTGGGAGAGCAGGGGCAGGCTGCTTCGGTC CCTGGAGGAGATCTTGGTGATGTCTCCTCCCCCAGAGGCATACCAGACAGCAAGGACAGA GTGGTTGCAGCGTGGATAGGAAGGACGATGAGGGAGCTTAAGCTGGCTGGCTTCCATGTC CTCAACCATGTGGGAGGTGAGGTCACGGTGCGAGCAAAGGGACGAAGCAGGTGGGGGCTC AGGAGATGGAGAGGTCTGGAACGGCTGCTGTGGGGAAGGCTGGGCTGGAGGTCGCGCGGG TGCTGCAGTGTTGTGAGCTCACGCTGCAGTGTTCAGTGATCTCTCCACTGCTTTCTGCAG CTTGGAAGCAGAAACAGGAAGAGGGTGGTGGTGTGACTTGGGGTTGGAGACTGGGCCGGA TAGCTGCGGGTGGCTGCAGGTGCCCGGAGGGACAGTGAACCCTGTAGGAGTTAGATGGTC ATGGGACCAGGCTGGGGCATGGTGGACAAAGTCCAGGGGTGGGTTGCGGGTGGGGGCAAC TAAGGCTTTTCTGGGTTCATGTAGTAGGTGTGGATGGGGAAGAGGAGAGGCAGATAATGG CTGGCAAGAGACTTGGAGGTAAATCTGAGGTCAAGGATGTCCCATGATGGATGATGACTG AGATGGACGGAAGTTTGGTTTGAAGCGGTGGCATTGGTGCAGGCTGGCAGAGGGGGCAGT TCTGGATAGAGTGTCCTGATGAATGGGGATACCCATGGGAGGTGATGCAGATGAGGATTC TGTGCTTCTGAAGGAGGAGCCAGGCATTTAGAATGGCACTGGAGAGCAAGGACTGACTGA GCCCCTTCACTGTGTCCCCAAGAGGCCAGGAAGGGAAGATTGGAGGAGACAAAGTTGAAG TGAGTGTTCCAGGGAACGAGTCAGTTAAGAGATGGTAGGATCTTAAGGGAAGATGGCTAA GATCTTAAGGGAAAATGGCTAAGATCTGGAGAGTTGGACTTATATGGACGCATGCTTCAC TGGGCAGAAAGGACGCAACTCTGGGTACAGATGGGGGTCGGGGTGAGGGGCAGTGAAGCC AGGGCTGAGGGGAGAGGGGCTATGGGAGGAGGTAGCAGGGGGGCTTTGGAGGTTCCAGGT GTTATGGGAATGAAGGCATCTGCAGGTAGCACACTCAGTGATGGGGCCACAGTCCTGGGT AGGCTTTTCCAGACATAGAAAAGACCCACCCAGTGCACTTGCTCCTGTGGGCGTGTCTCC CGGCAGTGCTGATGCAGGTCAGACAGCCCTTCCCGGAGTTCTCAGGGTTACCTCTCAGGG TTACTGGCAGCGCTGTCCTTAACATCCACCCCCCACTCCAGTCCCCGGGATCCCCTAAAT GGGAAGGTTGGGCTGGCCTAGGGGGTGGCCTTTGGACCTTCTCTGAGGCTGCTGGGGAGG GACCTGAGTGAGGTAGTTCAGAGGCCCCTCACTCGAGGGACAGGGTCTCTGTGTGGGGGT GGGGCTGGGTTCTTGCAGACAGCTCAGTGGGTTTAACCTGCAATTCCTGCCTGTGTTGTA TCCTCACGCTGACAGGGGCTGCTCAGCAGCAGGCAGGCCGGGTAGGTGTGTGTGCGCGTG TGTGCACGCCATTGCGTGCCCCTGTCCCATGGGGGCGATGTCCGAGCATGCTCTGTGGAG TTGATGCGTGGCCCTGGAGTGTCCGGTGCTTCAGTGACCCGAGCTGCTGTGTGCGTGGCC TCCGTCCGCCCAGTCATTCTGGCCTGTCTGTGACTGCTCAGGGGGTTTGGGCAGAGTGGG TGGAAATGTCTTGCTGTACGAGATCCAGGCTTAGGTCCCTTCCCCTGTTATTTGTGTGGT GCTGGGGATGGCGGGGGTAGGGGGACGAGGGAGAAGCTTTAAGGGTCAAGCCTGAGCATC TGGGACACGAGCTGGGAGCTAAGCCTCATCGGAAGAAGCCGGGTAGGCTGGCCTGGGAAG GTTCTTGGAGGCAGCAGCCCTCTAGAGTGTGAGGAAAATGTTGGGATTGCAGGTGCGCTC CCCTGGGGCCCCAGGGCCCCTGACTCTGAAGGAGGTGGAGGAGCTGGAGCAGCTGACCCA GCAGCTAATGCAGGACATGGAGCATCCTCAGAGGCAGAATGTGGCTGTCAACGGTGAGCC CACCCCACCGGGACACCCCCACCCTGCCCCCACATCACGGTGGGGGCCAGGGCTGTGGCT CCACTCCCTATCTGAGCTGGCTGATCCCTCGCAGCTCTACATACTTCCTTCTATTTACTG CTGTCTTCTCTGGCCTTCCCAGAACTCTGCGGCCGATGCCATCAACCCCTGGCCCGGGCG CAGCCAGCCGTCCGCGCTCTAGGGCAGCTGTTCCACATCGCCTGCTTCACCTGCCACCAG TGTGCGCAGCAGCTCCAGGGCCAGCAGTTCTACAGTCTGGAGGGGGCGCCGTACTGCGAG GGCTGTTACACTGTGAGTCGGGCTGTGCTGGGCTGTGCTGGGCTGTGCTGGGCAGTCGGG CCCTGGAAGCTTGCTGTGGGGTGCCGGTTCCCTGCCAACCTCCTCCTGCTGCCTCCTCAG GACACCCTGGAGAAGTGTAACACCTGCGGGGAGCCCATCACTGACCGCATGCTGAGGGCC ACGGGCAAGGCCTATCACCCGCACTGCTTCACCTGTGTGGTCTGCGCCCGCCCCCTGGAG GGCACCTCCTTCATCGTGGACCAGGCCAACCGGCCCCACTGTGTCCCCGACTACCACAAG TGAGGACCTGCCACCTGCCTTCTGGGTTCCCGGCGTGCTTGGTCTGGTAGCCCGGCTGCT TGCTACCCTAGCCTCAGGACAGCCCCAAACCCCTGGTGGTGTTTTCTGGTCCCATGTCCT GTCTGTAAACAGCAGGGACCAAGTCATCGGGATGTAGCTGTCCAGGGGCCTTAGGCCTGG GCATCGAGTCCTGCTGCTGTCTGGTCCCTCCCTCGCCCTTGATCACTGAAGCTTATTGTG GGTGTATGTCAGCATTTCGTGAAGTGTGCTGGAGTGACTTCATCTCACACACAGGCTGGG TTCTAAAAGTTCTTTTGGAGATCAGCTGTTTGGATTTCTGGTTTCTCCCCAGAAATAGTG TTTAGAAGGTGGCTACTTTTTCAGGCTGACCCGCAGAACCTCAGTGCAGCTGTGGGAACA GTGCAGAATCTGACCCCCACCTCTGACAGAGTGTTTGGGTAAACACTTTCAGGATTCCAT CTGGGGTGGCCACAACTTCACATCCCTCCACAGTGCCAGACAGTCAGGGCAGAGGCAACG TGCATGGGGGTGGGAGGATTGGGGGAAGGTGAGGGTCAGGGACCCAGGATGGGATGGGAG GGGTACCTCAGGGCTGGCTTTCTGCAGGAGCTGCAGTGTGAATGGGACAGTAAGGGTCGA GTGGGAGAGAACACCGTGGCAGGTGTGTGGGAGGCTCCCTTGCTTTGGGAGAGTGACTGG TGAGGCAGGAAATTCCCTTTGATGAGGGCCAGTCATGGTGTCTCACTCTTAGGCCCTTCT GGTGAGCTTCCTTCACCTGGAGATGCAGGGCAGAGAAGTCTGCTTCCTTGCTGCCCAACC TGGCTTATGCGTGCGCACACCGGGGATGAAAGCCCTGGCTAACTCGGCTGGCCCTTTCTG CCCCTTCCAGGCAGTACGCCCCGAGGTGCTCCGTCTGCTCTGAGCCCATCATGCCTGAGC CTGGCCGAGATGAGACTGTGCGAGTGGTCGCCCTGGACAAGAACTTCCACATGAAGTGTT ACAAGTGTGAGGTCAGCCATCCCTCTGGACTCCTTGGGCAGGTTCTGACCAGGAGGTGGC GGGAGATGCTGCTTACTAACTGGGAGGTGGAAAGCACCAGCATTCAGGAAACAGGGCTGT GATTTTGAGGGTGGCTCATGGTGGCACCCCATCTGTCCTGCCAGAATGCTTCCTGCCACT GCAGGAAATGGGGCTGTGGGGCTTCTGAGGTCACTTTGAGTCATGGATAAGCCAAGAAAT GGGACAAGCCAATAGGAGAGAAGAAGGGCATGGTGTTTTACCGTGGTAGGGGATGGGGAA ACAGGAGCTGAGAGAAGAGGTCTTCGAATGGAGGTGAGCCAACCTCTATTTTATTAGGGT GGTGGTGGGCAGGGGAGCAAGCACCTTGGGAGCAGCTCTACCCACTGCTTGCCCTCTTGC AGGAAGGTCCTAGTGGGTGACTGGAAGTAGGATAGGGATGGGGAGTTGGGTGTGGCTGGA AAAAGCGATGACACCAGCTCTGAGCCATGAAGCATCTTTCTAATTCCAAGATGGAGCTGG ATGGGGTGGGGTAGGGTGGAGCAGAGCAGGGGCCTTCCGGTCCAGTGCCCCTCACCCTTC CTTCTTCCCAGGACTGCGGGAAGCCCCTGTCGATTGAGGCAGATGACAATGGCTGCTTCC CCCTGGACGGTCACGTGCTCTGTCGGAAGTGCCACACTGCTAGAGCCCAGACCTGAGTGA GGACAGGCCCTCTTCAGACCGCAGTCCATGCCCCATTGTGGACCACCCACACTGAGACCA CCTGCCCCCACCTCAGTTATTGTTTTGATGTCTAGCCCCTCCCATTTCCAACCCCTCCCT AGCATCCCAGGTGCCCTGACCCAGGACCCAACATGGTCTAGGGATGCAGGATCCCCGCCC TGGGGTCTGGTCCTCGCCCATCCTGCAGGGATTGCCCACCGTCTTCCAGACACCCCACCT GAGGGGGGCACCAGGTTTAGTGCTGCTGCTTTCACTGCTGCACCCGCGCCCTCGGCCGGC CCCCCGAGCAGCCTTTGTACTCTGCTTGCGGAGGGCTGGGAGACCCTCCAGGACATTCCC ACCCTCCCCCATGCTGCCAAGTTGTAGCTATAGCTACAAATAAAAAAAAACCTTGTTTTC CAGAA OMIM ID 602002