Entrez gene ID | | 79048 |
Official gene symbol | | SECISBP2 |
Full name | | SECIS binding protein 2 |
Aliases | | ,DKFZp686C09169,SBP2, |
Gene summary | | The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. The gene described in this record encodes a nuclear protein that functions as a SECIS binding protein. Mutations in this gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism. [provided by RefSeq] |
Location | | Chromosome: 9 Locus: 9q22.2 |
Gene position | | 91933412 - 91974561 Map Viewer |
Gene orientation | | plus |
Gene size | | 41150 bp |
Gene sequence |
| |
OMIM ID | | 607693 |
|