Entrez gene ID | | 79577 |
Official gene symbol | | CDC73 |
Full name | | cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) |
Aliases | | ,C1orf28,FLJ23316,HPTJT,HRPT2,HYX, |
Gene summary | | This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1q25 |
Gene position | | 193091088 - 193223945 Map Viewer |
Gene orientation | | plus |
Gene size | | 132858 bp |
Gene sequence |
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OMIM ID | | 607393 |
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