Entrez gene ID | | 79661 |
Official gene symbol | | NEIL1 |
Full name | | nei endonuclease VIII-like 1 (E. coli) |
Aliases | | ,FLJ22402,FPG1,NEI1,hFPG1, |
Gene summary | | NEIL1 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).[supplied by OMIM] |
Location | | Chromosome: 15 Locus: 15q24.2 |
Gene position | | 75639331 - 75647588 Map Viewer |
Gene orientation | | plus |
Gene size | | 8258 bp |
Gene sequence |
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OMIM ID | | 608844 |