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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CALD1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID800
Official gene symbolCALD1
Full namecaldesmon 1
Aliases,CDM,H-CAD,HCAD,L-CAD,LCAD,MGC21352,NAG22,
Gene summaryThis gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq]
LocationChromosome: 7   Locus: 7q33
Gene position134464164 - 134655480  Map Viewer
Gene orientationplus
Gene size191317 bp
Gene sequence
OMIM ID114213