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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for RNF34 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID80196
Official gene symbolRNF34
Full namering finger protein 34
Aliases,CARP-1,CARP1,FLJ21786,RFI,RIF,RIFF,hRFI,
Gene summaryThe protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]
LocationChromosome: 12   Locus: 12q24.31
Gene position121837902 - 121862155  Map Viewer
Gene orientationplus
Gene size24254 bp
Gene sequence
OMIM ID608299