Entrez gene ID | | 80267 |
Official gene symbol | | EDEM3 |
Full name | | ER degradation enhancer, mannosidase alpha-like 3 |
Aliases | | ,C1orf22, |
Gene summary | | Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins. EDEM3 belongs to a group of proteins that accelerate degradation of misfolded glycoproteins in the ER (Hirao et al., 2006 [PubMed 16431915]).[supplied by OMIM] |
Location | | Chromosome: 1 Locus: 1q24-q25 |
Gene position | | 184724041 - 184659625 Map Viewer |
Gene orientation | | minus |
Gene size | | 64417 bp |
Gene sequence |
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OMIM ID | | 610214 |