Entrez gene ID | | 8091 |
Official gene symbol | | HMGA2 |
Full name | | high mobility group AT-hook 2 |
Aliases | | ,BABL,HMGI-C,HMGIC,LIPO,STQTL9, |
Gene summary | | This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq] |
Location | | Chromosome: 12 Locus: 12q15 |
Gene position | | 66218240 - 66360071 Map Viewer |
Gene orientation | | plus |
Gene size | | 141832 bp |
Gene sequence |
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OMIM ID | | 600698 |
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