Database of mammalian genes
Home

Home Search Browse RAGs User guide FAQs Links Questions Contribute

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for HM13 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID81502
Official gene symbolHM13
Full namehistocompatibility (minor) 13
Aliases,H13,IMP1,IMPAS,MSTP086,PSENL3,PSL3,SPP,dJ324O17.1,
Gene summaryThe protein encoded by this gene, which localizes to the endoplasmic reticulum, catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein. This activity is required to generate signal sequence-derived human lymphocyte antigen-E epitopes that are recognized by the immune system, and to process hepatitis C virus core protein. The encoded protein is an integral membrane protein with sequence motifs characteristic of the presenilin-type aspartic proteases. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 20   Locus: 20q11.21
Gene position30102241 - 30157370  Map Viewer
Gene orientationplus
Gene size55130 bp
Gene sequence
OMIM ID607106