Entrez gene ID | | 81502 |
Official gene symbol | | HM13 |
Full name | | histocompatibility (minor) 13 |
Aliases | | ,H13,IMP1,IMPAS,MSTP086,PSENL3,PSL3,SPP,dJ324O17.1, |
Gene summary | | The protein encoded by this gene, which localizes to the endoplasmic reticulum, catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein. This activity is required to generate signal sequence-derived human lymphocyte antigen-E epitopes that are recognized by the immune system, and to process hepatitis C virus core protein. The encoded protein is an integral membrane protein with sequence motifs characteristic of the presenilin-type aspartic proteases. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 20 Locus: 20q11.21 |
Gene position | | 30102241 - 30157370 Map Viewer |
Gene orientation | | plus |
Gene size | | 55130 bp |
Gene sequence |
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OMIM ID | | 607106 |
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