Entrez gene ID | | 8189 |
Official gene symbol | | SYMPK |
Full name | | symplekin |
Aliases | | ,FLJ27092,SPK,SYM, |
Gene summary | | This gene encodes a nuclear protein that functions in the regulation of polyadenylation and promotes gene expression. The protein forms a high-molecular weight complex with components of the polyadenylation machinery. It is thought to serve as a scaffold for recruiting regulatory factors to the polyadenylation complex. It also participates in 3'-end maturation of histone mRNAs, which do not undergo polyadenylation. The protein also localizes to the cytoplasmic plaques of tight junctions in some cell types. [provided by RefSeq] |
Location | | Chromosome: 19 Locus: 19q13.3 |
Gene position | | 46366548 - 46318700 Map Viewer |
Gene orientation | | minus |
Gene size | | 47849 bp |
Gene sequence |
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OMIM ID | | 602388 |
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