Entrez gene ID | | 81890 |
Official gene symbol | | QTRT1 |
Full name | | queuine tRNA-ribosyltransferase 1 |
Aliases | | ,FP3235,TGT, |
Gene summary | | tRNA-guanine transglycosylase (TGT; EC 2.4.2.29) synthesizes queuosine (Q), which is found in tRNAs that recognize NAU and NAC codons, encoding tyr, asn, asp, and his. Prokaryotic TGT is a single protein of 43 kD. In contrast, mammalian TGT appears to be a heterodimer consisting of a 60-kD subunit (USP14; MIM 607274) and a 43-kD catalytic subunit (QTRT1) (Deshpande and Katze, 2001 [PubMed 11255023]).[supplied by OMIM] |
Location | | Chromosome: 19 Locus: 19p13.3 |
Gene position | | 10812112 - 10824043 Map Viewer |
Gene orientation | | plus |
Gene size | | 11932 bp |
Gene sequence |
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OMIM ID | | 609615 |
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