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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for KLRC4 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 8302 Official gene symbol KLRC4 Full name killer cell lectin-like receptor subfamily C, member 4 Aliases ,FLJ17759,FLJ78582,NKG2-F,NKG2F, Gene summary Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. KLRC4 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. The 3' end of the KLRC4 transcript includes the first non-coding exon found at the 5' end of the adjacent D12S2489E gene transcript. [provided by RefSeq] Location Chromosome: 12   Locus: 12p13.2-p12.3 Gene position 10562356 - 10559983  Map Viewer Gene orientation minus Gene size 2374 bp Gene sequence >KLRC4:complement(3320107..3322480):Length=2374 TAAAACTTTAGGAAATTAGTACCAGACTTTTATATTGGTCAACAGCAAAATGAACATTAC TACTCAGCCTCCAACACATGCAGTTTGCCTATACCAGGGATCCTGTCAAAATATACACCA CTTATAGCTTCTTAAGTGCAGTTATCATAGAGCACAGTCCCTGACATCACACAGCTGCAG AGATGAATAAACAAAGAGGAACCTACTCAGAAGTGAGTCTGGCCCAGGACCCAAAGAGGC AGCAAAGGAAACTTAAGGGCAATAAAATCTCCATTTCAGGAACCAAACAGGAAATATTCC AAGTAGAATTAAACCTTCAAAATGCTTCTTCGGATCATCAAGGGAATGACAAGACATATC ACTGCAAAGGTAAAACATTAAATAGATCTTCAATATTATTGTTCTAGGATGTGCAGTTGA ATGCAGAAAGGTGGGGAAAGATTAGGGAATATTTTGCACTTGTGAGAATCAGAGGTCAAA GTCAGGATCTAATATTCTAATATGAAATCTGAAGCCTGATTTTATTCAGGCATTGTTCAA TTGTAATTTGTGATTAACAACTCATGGAGCATTATATTTACTGATAATGAAATGGTATAT TCTGAGAGAAAGATTACTAGAGTAGATGTAGATTTAGAGGACAGAGTTTATCATTATGTT TTCCTGTGCACGTGAGTTCTCTTGTACGTAAACCTTCTCATCAACTCTCTATCTCCCCTC TCTCAGTGCCTCTTTCTCTCCCTGCAGGTTTACTGCCACCTCCAGAGAAGCTCACTGCTG AGGTCCTAGGAATCATTTGCATTGTCCTGATGGCCACTGTGTTAAAAACAATAGTTCTTA TTCCTTGTAAGCATATTCTTGAAAGATTATAAGGGAACTTTTCACTATAATGATTGGAAG CGCCTTGAAACATTTCATAATAATGAGGATTAGAATTCTCTGTTTAATGTATATCTCTGA ACCCCAAGATAATATGCTGCTTCTGAACTTTTCAAATTTATAAATAACAGAATAATTGTA GAAAACATTTATTTTTTTGTGTGTACTAAATATATATGTATATATGATACACACACAGAG AGATGTATTCTGATTTCATGACTCAAAGACATGTTTTAAGAGAAAAAATATTTAGAAAAA CAAATTAATTTTTGAAAGTGGTTAGATCAAATACTATAAGAGATGGTGAAGTTTTATGCT AATGGCTTTAAAAATATTTGTTTTAAAGATCTCATTATTTTTATAGAAAAGTCATTTTTA TTTCAGATTGTTCCAATTTAAAATAATTTTAAATTTTGTATTTCAAAGTAAGCAACTGAA TTTATTATAATTTGTCTAGATATTAATTTTGTAAGAATCACTTTAATTTTTCTAGGTATT GGAGTACTGGAGCAGAACAATTTTTCCCTGAATAGAAGAATGCAGAAAGGTACATTATGA TTGTCAATGTTCTGATGTTAGTACAGTTTATATTTTGTCTCTAAAGGGATGCAAAATGAT AATAAAATGTTTTGGGAAAATAAACTATAACAATGAGCCATAAATGTTTATAAAATAAAG ATTATATGAGGGCATGTCCTTTTCTCCAATAATAAGTAGAAATGCTCAGTTAAAATCATT ATACCCTCTTGTTGCATTTAATTAACTGAAATTTCCTACTACTATAAGATGATAAGAGAT AAATAATTTTACTATACTTAAAAAGCAGTTTTGTTCAGTGATGTTTAAGATGTGTAGGGT GGATTTTTGTTGGCGGGCTTGTTTTGTATGGGAACACAATTAAGGGATGAGAGGTGGACC TTTTATTGTGCATGTGCGTATGAGTGACTCGTTATTTTAAAATATATATTTAACAACTTA TGAGGATGCAGATATTGTGTACCTGTATGTTTATAGCTTTGCAAATATATAAAATAATTT TCATTTGTAAACATATTGTTTTGCATAGTAATTCATATTTTTATTTAGCACGTCATTGTG GCCATTGTCCTGAGGAGTGGATTACATATTCCAACAGTTGTTATTACATTGGTAAGGAAA GAAGAACTTGGGAAGAAAGAGTTTGCTGGCCTGTGCTTCGAAGAACTCTGATCTGCTTTC TATAGATAATGAGGAAGAAATGGTAAGACGTAAATGTTTCAACACTTTACTAAAAGCTTA TTTCTGTCAATATCATATTTGTAGAAATCATCCATATGTTTATACATATATTTACTTCAT ATATTTTTAAGTCTGTGTAGTATTCAACTGACTTCATAATATTTTTATATTCATATACTG TTAATGCACATTTGGTTATTTCCAGTTTTGCTTTTCATGGAAACCCATGCTTCTATAAAT GTTTTTATCACAAAATAAATATAAAGAAAACTAA OMIM ID 602893