Entrez gene ID | | 83540 |
Official gene symbol | | NUF2 |
Full name | | NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae) |
Aliases | | ,CDCA1,CT106,NUF2R, |
Gene summary | | This gene encodes a protein that is highly similar to yeast Nuf2, a component of a conserved protein complex associated with the centromere. Yeast Nuf2 disappears from the centromere during meiotic prophase when centromeres lose their connection to the spindle pole body, and plays a regulatory role in chromosome segregation. The encoded protein is found to be associated with centromeres of mitotic HeLa cells, which suggests that this protein is a functional homolog of yeast Nuf2. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1q23.3 |
Gene position | | 163291723 - 163325553 Map Viewer |
Gene orientation | | plus |
Gene size | | 33831 bp |
Gene sequence |
| |
OMIM ID | | 611772 |
|