Entrez gene ID | | 83941 |
Official gene symbol | | TM2D1 |
Full name | | TM2 domain containing 1 |
Aliases | | ,BBP, |
Gene summary | | The protein encoded by this gene is a beta-amyloid peptide-binding protein. It contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily and known to be important in heterotrimeric G protein activation. Beta-amyloid peptide has been established to be a causative factor in neuron death and the consequent diminution of cognitive abilities observed in Alzheimer's disease. This protein may be a target of neurotoxic beta-amyloid peptide, and may mediate cellular vulnerability to beta-amyloid peptide toxicity through a G protein-regulated program of cell death. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1p31.3 |
Gene position | | 62191095 - 62146719 Map Viewer |
Gene orientation | | minus |
Gene size | | 44377 bp |
Gene sequence |
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OMIM ID | | 610080 |
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