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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TM2D1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID83941
Official gene symbolTM2D1
Full nameTM2 domain containing 1
Aliases,BBP,
Gene summaryThe protein encoded by this gene is a beta-amyloid peptide-binding protein. It contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily and known to be important in heterotrimeric G protein activation. Beta-amyloid peptide has been established to be a causative factor in neuron death and the consequent diminution of cognitive abilities observed in Alzheimer's disease. This protein may be a target of neurotoxic beta-amyloid peptide, and may mediate cellular vulnerability to beta-amyloid peptide toxicity through a G protein-regulated program of cell death. [provided by RefSeq]
LocationChromosome: 1   Locus: 1p31.3
Gene position62191095 - 62146719  Map Viewer
Gene orientationminus
Gene size44377 bp
Gene sequence
OMIM ID610080