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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CUL4B (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID8450
Official gene symbolCUL4B
Full namecullin 4B
Aliases,DKFZp686F1470,KIAA0695,MRXHF2,MRXSC,SFM2,
Gene summaryThis gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: X   Locus: Xq23
Gene position119709684 - 119658444  Map Viewer
Gene orientationminus
Gene size51241 bp
Gene sequence
OMIM ID300304