Entrez gene ID | | 8450 |
Official gene symbol | | CUL4B |
Full name | | cullin 4B |
Aliases | | ,DKFZp686F1470,KIAA0695,MRXHF2,MRXSC,SFM2, |
Gene summary | | This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: X Locus: Xq23 |
Gene position | | 119709684 - 119658444 Map Viewer |
Gene orientation | | minus |
Gene size | | 51241 bp |
Gene sequence |
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OMIM ID | | 300304 |
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