Entrez gene ID | | 8456 |
Official gene symbol | | FOXN1 |
Full name | | forkhead box N1 |
Aliases | | ,FKHL20,RONU,WHN, |
Gene summary | | Mutations in the winged-helix transcription factor gene at the nude locus in mice and rats produce the pleiotropic phenotype of hairlessness and athymia, resulting in a severely compromised immune system. This gene is orthologous to the mouse and rat genes and encodes a similar DNA-binding transcription factor that is thought to regulate keratin gene expression. A mutation in this gene has been correlated with T-cell immunodeficiency, the skin disorder congenital alopecia, and nail dystrophy. Alternative splicing in the 5' UTR of this gene has been observed. [provided by RefSeq] |
Location | | Chromosome: 17 Locus: 17q11-q12 |
Gene position | | 26850959 - 26865175 Map Viewer |
Gene orientation | | plus |
Gene size | | 14217 bp |
Gene sequence |
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OMIM ID | | 600838 |
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