Entrez gene ID | | 8476 |
Official gene symbol | | CDC42BPA |
Full name | | CDC42 binding protein kinase alpha (DMPK-like) |
Aliases | | ,DKFZp686L1738,DKFZp686P1738,FLJ23347,KIAA0451,MRCK,MRCKA,PK428, |
Gene summary | | The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1q42.11 |
Gene position | | 227505826 - 227177566 Map Viewer |
Gene orientation | | minus |
Gene size | | 328261 bp |
Gene sequence |
| |
OMIM ID | | 603412 |
|