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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for RAE1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID8480
Official gene symbolRAE1
Full nameRAE1 RNA export 1 homolog (S. pombe)
Aliases,FLJ30608,MGC117333,MGC126076,MGC126077,MIG14,MRNP41,Mnrp41,dJ481F12.3,dJ800J21.1,
Gene summaryMutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
LocationChromosome: 20   Locus: 20q13.31
Gene position55926145 - 55953519  Map Viewer
Gene orientationplus
Gene size27375 bp
Gene sequence
OMIM ID603343