Entrez gene ID | | 85437 |
Official gene symbol | | ZCRB1 |
Full name | | zinc finger CCHC-type and RNA binding motif 1 |
Aliases | | ,MADP-1,MADP1,MGC26805,RBM36,ZCCHC19, |
Gene summary | | Pre-mRNA splicing is catalyzed by the spliceosome. U12-type spliceosome binds U12-type pre-mRNAs and recognizes the 5' splice site and branch-point sequence. U11 and U12 snRNPs are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron. The protein encoded by this gene contains a RNA recognition motif. It was identified as one of the protein components of U11/U12 snRNPs. This protein and many other U11/U12 snRNP proteins are highly conserved in organisms known to contain U12-type introns. These proteins have been shown to be essential for cell viability, suggesting the key roles in U12-type splicing. [provided by RefSeq] |
Location | | Chromosome: 12 Locus: 12q12 |
Gene position | | 42719932 - 42705888 Map Viewer |
Gene orientation | | minus |
Gene size | | 14045 bp |
Gene sequence |
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OMIM ID | | 610750 |