Entrez gene ID | | 8550 |
Official gene symbol | | MAPKAPK5 |
Full name | | mitogen-activated protein kinase-activated protein kinase 5 |
Aliases | | ,PRAK, |
Gene summary | | The protein encoded by this gene is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq] |
Location | | Chromosome: 12 Locus: 12q24.12-q24.13 |
Gene position | | 112280279 - 112331228 Map Viewer |
Gene orientation | | plus |
Gene size | | 50950 bp |
Gene sequence |
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OMIM ID | | 606723 |
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