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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for YARS (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID8565
Official gene symbolYARS
Full nametyrosyl-tRNA synthetase
Aliases,CMTDIC,TYRRS,YRS,YTS,
Gene summaryAminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine. [provided by RefSeq]
LocationChromosome: 1   Locus: 1p35.1
Gene position33283633 - 33240840  Map Viewer
Gene orientationminus
Gene size42794 bp
Gene sequence
OMIM ID603623