Entrez gene ID | | 8611 |
Official gene symbol | | PPAP2A |
Full name | | phosphatidic acid phosphatase type 2A |
Aliases | | ,LLP1a,LPP1,PAP-2a,PAP2,PAP2a2,PAP2alpha2,PAPalpha1, |
Gene summary | | The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is an integral membrane glycoprotein, and has been shown to be a surface enzyme that plays an active role in the hydrolysis and uptake of lipids from extracellular space. The expression of this gene is found to be regulated by androgen in a prostatic adenocarcinoma cell line. At least two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq] |
Location | | Chromosome: 5 Locus: 5q11 |
Gene position | | 54830873 - 54720682 Map Viewer |
Gene orientation | | minus |
Gene size | | 110192 bp |
Gene sequence |
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OMIM ID | | 607124 |
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