Entrez gene ID | | 8643 |
Official gene symbol | | PTCH2 |
Full name | | patched homolog 2 (Drosophila) |
Aliases | | ,PTC2, |
Gene summary | | This gene encodes a transmembrane receptor of the patched gene family. The encoded protein may function as a tumor suppressor in the hedgehog signaling pathway. Alterations in this gene have been associated with nevoid basal cell carcinoma syndrome, basal cell carcinoma, medulloblastoma, and susceptibility to congenital macrostomia. Alternatively spliced transcript variants have been described. |
Location | | Chromosome: 1 Locus: 1p33-p34 |
Gene position | | 45308616 - 45285516 Map Viewer |
Gene orientation | | minus |
Gene size | | 23101 bp |
Gene sequence |
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OMIM ID | | 603673 |
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