Entrez gene ID | | 8685 |
Official gene symbol | | MARCO |
Full name | | macrophage receptor with collagenous structure |
Aliases | | ,SCARA2, |
Gene summary | | The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains. [provided by RefSeq] |
Location | | Chromosome: 2 Locus: 2q12-q13 |
Gene position | | 119699745 - 119752236 Map Viewer |
Gene orientation | | plus |
Gene size | | 52492 bp |
Gene sequence |
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OMIM ID | | 604870 |
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