Entrez gene ID | | 8729 |
Official gene symbol | | GBF1 |
Full name | | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
Aliases | | ,ARF1GEF,FLJ21263,FLJ21500,KIAA0248,MGC134877,MGC134878, |
Gene summary | | This gene encodes a member of the Sec7 domain family. The encoded protein is a guanine nucleotide exchange factor that regulates the recruitment of proteins to membranes by mediating GDP to GTP exchange. The encoded protein is localized to the Golgi apparatus and plays a role in vesicular trafficking by activating ADP ribosylation factor 1. The encoded protein has also been identified as an important host factor for viral replication. Multiple transcript variants have been observed for this gene. [provided by RefSeq] |
Location | | Chromosome: 10 Locus: 10q24 |
Gene position | | 104005309 - 104142649 Map Viewer |
Gene orientation | | plus |
Gene size | | 137341 bp |
Gene sequence |
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OMIM ID | | 603698 |