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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for GBF1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID8729
Official gene symbolGBF1
Full namegolgi brefeldin A resistant guanine nucleotide exchange factor 1
Aliases,ARF1GEF,FLJ21263,FLJ21500,KIAA0248,MGC134877,MGC134878,
Gene summaryThis gene encodes a member of the Sec7 domain family. The encoded protein is a guanine nucleotide exchange factor that regulates the recruitment of proteins to membranes by mediating GDP to GTP exchange. The encoded protein is localized to the Golgi apparatus and plays a role in vesicular trafficking by activating ADP ribosylation factor 1. The encoded protein has also been identified as an important host factor for viral replication. Multiple transcript variants have been observed for this gene. [provided by RefSeq]
LocationChromosome: 10   Locus: 10q24
Gene position104005309 - 104142649  Map Viewer
Gene orientationplus
Gene size137341 bp
Gene sequence
OMIM ID603698