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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TNFSF14 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 8740 Official gene symbol TNFSF14 Full name tumor necrosis factor (ligand) superfamily, member 14 Aliases ,CD258,HVEML,LIGHT,LTg,TR2, Gene summary The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported. [provided by RefSeq] Location Chromosome: 19   Locus: 19p13.3 Gene position 6670599 - 6663148  Map Viewer Gene orientation minus Gene size 7452 bp Gene sequence >TNFSF14:complement(6603148..6610599):Length=7452 CGAGACTCCATCTCAAAAACAAAACAAATAAACGAACAAAAAAACCCACAACGTATTATT TTCTTGTTTACGAGGTTTCTTGTCTCTCTGGCTCCACCAGAAGAGGAGCAGGGACCCTTC TTGCTGTTGTTCATTGCTGCATCCCCCACACCGAGAGCAGAGCCTGGCATGGGCAGAAAG TCCTCAGTCGATATTTGGTGGCCCCAAGCGAATGAAGCATCCAAGAAGGGAAAGCTGGGG GCTCCCCACTGCACTTGCCACCTGAGTCACATTTTCAGAAGCCTCTGGAAAGTGTGAGAG TCTGTATGAGTGAGAGTGAGACAGGGCCAAGACCGGGGGCGGCGGGTACCGGAAGAAGAG GAGGGTGAGTGGGGGAAGGGGTGGGGCTGAACCCCAGCTCTAAAGGCGGCCCACGGGTGC CTGTCCGCAGCGTGCACAGCCCAGGAGTGTTGAGCAATTTCGGTTTCCTCTGAGGTTGAA GGACCCAGGCGTGTCAGCCCTGCTCCAGACACCTTGGGCATGGAGGAGAGTGTCGTACGG CCCTCAGTGTTTGTGGTGGATGGACAGACCGACATCCCATTCACGAGGCTGGGACGAAGC CACCGGAGACAGTCGTGCAGTGTGGCCCGGGTGGGTCTGGGTCTCTTGCTGTTGCTGATG GGGGCCGGGCTGGCCGTCCAAGGCTGGTTCCTCCTGCAGCTGCACTGGCGTCTAGGAGAG ATGGTCACCCGCCTGCCTGTGAGTGGGACCGGGGGGCTGAGAGCAGGTGGAGGTGAGGGG GGCTCCCCTGTGTCATTGTGGGTCACTGTGTGTCTGTGTGTGTGTGTGTGTGTGTGTGTG TGTGTGTGTGTAGGACAGGGCACAGGCTGAGAGCAGCTGGCTTGACTGGTTGCTGCTCCC AGCCTTGGGCAAGTGAATTCACCTCTCTGAACCTCAGTGTCTTCATCTACAAAATAAGGG CAGTCTCTTCATAGGGGACGAAGTATGCTATGGCATGTGTAGTACCAGACGATGCCAGCT CCACCCGTCGGAACTGACACCCCAACACTGCCATGCACACCCCTGTGCACACACGCATGC ATTTTCTCTGTACTTTTTTATTTTTGAGACGGAGTTTCACTCTCGTTGCCCAGGCTGGAG TGCAATGGCATGATCTCTGCTCACCGCAACCTCTGCCTCCCGGGTTCAAGTGATTCTCCT GCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCATGCGCCACCACGCCTGGCCAATTTTG TATTTTTAGTAGAGATGGGGCTTCTCTATGTTTGTCAGGCTGGTCTCAAACTCCCGACCT CAGGAGATCCACCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACTGCG CCTGGCCTTCTCTGGTACTCTTATTACTGTTACTGCGATTGTCATTAATTCTCTGACCAT TTCCATCTGTGGAAATTTCTCGGTCTGCTTCCAGCTGGCTGTGGATGTGTCCGCCTGTCT GTGTGCCTCACCTGGGGGTCTATGTGTGCCCAACACCATACCCCTGTGGGCTTGGCCCCT TTTGTGTCCTGGGTCTGGATCCGGTGGCCACACATTCGTGTCCATATACCCATGTGGACG TATGTGCGTGTACCCACATGTCCACACACCCGCCTAGCTGCAGCCGGTGTATTCACGTTG TCTGTCTTTGTCTCTGGGTCTCTGTGTCTGTAGACGCACATGGATCCATAAACCACAAAC CACATGTCCACGCATCTGAGCCCACATGTGTCTTCTCAGCGTCATGATGATGTTGAGGTC TGTGCCCTGTGGCAGGTGCTATATCCCAAGGGTGGTGTCCATGTGTCCAGCCATCTCGCT GTCTGCATTTTTTTTTTTTTGAGACAAGGTTTCTCTCCCATAGCCCAGGCTGTAGTGTAG TGGTGCAGTCTTGGCTCACTACAACCCCACCTCCCAGGTTCAAGTGATTCCCTTGTCTCA GCCTCCTGAGCAGTAGCTGGGATCACAGGCATCCGCCACCGTGCCTGGCTAATTTGTGTA TTTTTAGTACAGACGGGGTTTCACCATGTTGGCCAGACTTGTCTCGAACTCCTGACCTCA AGTGATCCACCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCACGCC TGGCCTTGTCCCTGTATTTTTAAATATTACTTATTTATTTAATTAATTACATATTTATTT ATCTTAGAGACTGTGTCTCACTCTGCTTCCCAGGCTAGAGTGGAGTGGCACGATCATAGC TCACTGCAGCCTTGAACTCCTGGGCTCAAGCAAGCCTCCTGTCCCAGCTTCATGAGTAGC TGGGACTACAGGCATGCACCACCATGCCTGGCTAATCTTAAAAATTTTTTGTAGAGATGA GGTCTTGTTGTGTTGCCCAGGCTGGTCTTAAACTCCTGGCCTCAAGCTGTCCTCCCACTT TGGCCTCCCAAAGTGCTGGGATTACAGGTGTAAGCCACTGCTCTGGGCAATGTTATTTAT TTATTAAACCCTTTTATTTATTTATTTATTTTTTGAGATAGAATCTCACTCTGTCACCTA GGCTAGAGTGCAGTGGCACAATCTGGGCCCACTGCAACCTCCCAGGTTCAAGCGATCCTC CTGCCTCAGCCTCCAGAGCAGCTGGGATTACAGGCACCCACCACCAGGCCCAGCTAATTT TTGTAGTTTTAGTAGATACAGGGTTTTACTGTGTTGGCCAGGCTGGTCTCGAACTCCTGA CCTCAGGTAATCTGCCCACCTCGGCCTCCCGAAGTGCTGGGATTAGAGGTGTGAGCCAAT GCACCCGACCTATTAAACCTTTCTCTAGTGCATACTATGTGCCAAGCACTGTAATAATGC CTTACATATGTGAATTCATTAAACGCCAAGCAGACACGATTCGTAACTCCATTTACATAG AGGGAAACTGAGGCACCAAGTGGTTGTGAGGCCTCTGGACAGGGGGTGTGTGTCTGCAAG TGAGAGTATGTGGCCCTGTGTACGTGTCTGAGGGTGGTGTCGGTGGCTATGGTCCTCATG TCTCATAGCCATGTGTGAGCAATGCGAGGGCGTGGCCCCCGCTGCAGGTTCTTACCGCAG GCCCCTTCTGCATTTTCAGGACGGACCTGCAGGCTCCTGGGAGCAGCTGATACAAGGTGA GTCAGGGTCCTGGCCCCAGGGAAGGAGGTGTGATGATTCCCATGCCACCCCCACCCCTCG GTCAATTGCCCAATATGATTTGCACAACTGGCCAAATCCTCACAGGTGCCCCTCCCCCAG GCCTGAGAAGCAGAAGTTTGGGTCACTCCGGAAGGGGTGGGGTTGATTCCAGGAGGTGTA CACGGTGGCCCTTTAGGAGGCTGGCTTTTTACCTCCACTGTCTTCGTCTCTAACCTCTGA CCCTCTTTCCCCAGAGCGAAGGTCTCACGAGGTCAACCCAGCAGCGCATCTCACAGGTGA GAGGGACCCTGGATCCTGGCAAGGGGCAGGGGTCAGGGCGTCTCGGGAAGACCAGATAAA CGCCATACATATCAGTGTATTCATTCATTCATTGCTTATTTACTCACAGAGTTGCTCAGA ACATAGGCTGCAAGTGCTATGTATTTCCAGTTTTATTTATTTTATTATTTTTTATTTCTA TTTATTTATTTATTTATTTATTTATTTATTTTTGAGACAGTCTCACTCTGTTGCCCAGGC TGGGGTGCAGTGGCATGATCTCGGCTCACTGCAGTCTTCGCCTCCCGGGTTCAAGCGATT CTTCTGCCTCAGCCTCCCAAGTACCTGGGATTACAGGCATGCACCACCACACCCGGTTAA TTTTGTTGTATTTTTAGTAGAGACAGGGTTTTGCCATGTTGGCCAGGCTGGTCTCAAACT CCCGATCTCAGGTGATCCTCCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAG CCACCGGGCCCGGCCTAGTTTTATTAATTTAATGAACTCTCATATAGTGCTTATGCTGTG TTATGTGCTGTGACACGCTTTCTACATATTAATTCATTACATTCCAAGCAGGTGCTATTA ATATGCGCATTTTACAGAGAGGGAAACTGAGGCACACAGCGAGTACGAGGTGCCGCTTTG GTTTCTTGGTTTTGCAAACTTGCATGTTTGGACATTTTTTTTTTTTTTTTTTGAGACAGG GTCTTACTCTGTCAACTAGGCTGGAGTGGTGCTATCACGGCTCACGGCACCCTCAACTTG CCAGGTGCAAGCGATCCTCCCACTTCAGCTTCCCCAGCAGCTGGGACTACAGGTGCCTGC CACCATGCCCAGCTAATTTTTTTGTTTTTTGTAGAGACAGGGTCTCCCTATGTTACTTCA TCTGGAACTCCTGGACTCAAACTCCTGGGCTCAGGGGATCTTCCTGTCTCAGCCTCCCAA AGTGCTGGGATTATAGGGGTGAGACGCCACACCCAGCCAAGTTTTGACACTTTTGGCAAA TCACTTAACGGTTCCATGCCTCAGTTTCCCCACCTGCAAAAGAGGGATGCAAAGAGTTGA GATATAGACTAAGCAAGTTAATTTGCTTCCCTGTGCCTCAGTTTCCCTCCTCTGCAAAGC AGGGATAAAGCAAATTAATACATACAAACAGGCTAGGCAGGGTGGTGGCTCATGACTGGA ATCCCAGCACTTGGGAGCCTGAAGGATCGGTTGAGCACAGGAATTCGAGACCAGCCTGGG CCACATTGTGAGACCCCCACCTCTACAAACACACACACACACACACACACACACACACAC ACACGCACACATGCACACACACACACAAACAGCCTAGTGGTGACTGGCCTGGAGTCACAC AGCAGGAGTAAGACATGTGAGGCCGGGCGTGGTGGCTCACACCTGTAATCCCAGCACTCT GGGAGGCCGAGGCGGGTGGATCACCTGAAGTCAGGAGTTCAAGACCAGCCTCAGCAACAT GGCAAAACCCCATCTCTACTAAAACTACAAAAAGTAACTGGGTGCGGTGGCGGGCACCTG TAGTCCCAGCTACTCAGGAGACTGAAGCAGGACAATCGCTTGAACCTGGGAGGCGGAGGG TGCAGTAAGCCGAGATCATGCCACCACACTCCAGCCTGGTCCACAGAGCGAGACTCTGTG TCAAACAAACAAACAAACAAGCAACAGAGGAAGACATGTGCTGACCGGCAGCCCCCTTTG TCTCTCTCTTCCCAACAGGGGCCAACTCCAGCTTGACCGGCAGCGGGGGGCCGCTGTTAT GGGAGACTCAGCTGGGCCTGGCCTTCCTGAGGGGCCTCAGCTACCACGATGGGGCCCTTG TGGTCACCAAAGCTGGCTACTACTACATCTACTCCAAGGTGCAGCTGGGCGGTGTGGGCT GCCCGCTGGGCCTGGCCAGCACCATCACCCACGGCCTCTACAAGCGCACACCCCGCTACC CCGAGGAGCTGGAGCTGTTGGTCAGCCAGCAGTCACCCTGCGGACGGGCCACCAGCAGCT CCCGGGTCTGGTGGGACAGCAGCTTCCTGGGTGGTGTGGTACACCTGGAGGCTGGGGAGA AGGTGGTCGTCCGTGTGCTGGATGAACGCCTGGTTCGACTGCGTGATGGTACCCGGTCTT ACTTCGGGGCTTTCATGGTGTGAAGGAAGGAGCGTGGTGCATTGGACATGGGTCTGACAC GTGGAGAACTCAGAGGGTGCCTCAGGGGAAAGAAAACTCACGAAGCAGAGGCTGGGCGTG GTGGCTCTCGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCAGGCGGATCACCTGAGGT CAGGAGTTCGAGACCAGCCTGGCTAACATGGCAAAACCCCATCTCTACTAAAAATACAAA AATTAGCCGGACGTGGTGGTGCCTGCCTGTAATCCAGCTACTCAGGAGGCTGAGGCAGGA TAATTTTGCTTAAACCCGGGAGGCGGAGGTTGCAGTGAGCCGAGATCACACCACTGCACT CCAACCTGGGAAACGCAGTGAGACTGTGCCTCAAAAAAAAGAAAGGAAGAAAAAAGAAAA CTCAGGAAACAGATCTTGGGGGACACTCCAGGGAACCCAAAACTCAAAGGCGGAGAGCTC AGTGGGCACCACCAAGGCGAGATGAAGCCCCAGCAGGCACCTTCAGAAGACCCACGTAGA CTGCAGACCCTGCCACGGACAATACTAAGGACAAAAACCCAGAGACTTGGGGTCTGTGGG CCCCCAAACATGGGGTAAAGTTGATTTGCCTGATATTCAGGAAGAAGGGGTGAGGGGTGG GTATTTATGCTTTTGATTCAGAAGAAAGTGGGGCTTGGGATTCCAGGGACTTGGCTGGGG GTGGGAAACTTCATCCACTTCCCTACTCTCATCATGAGTACGGACAGGGTGGGCGGGAGA CTGATCATCGGGACTCATCATGAAGAGCCCAGCCCCACCCCACATACTCAGATCCCACCC ACAGACTGGTGGCCACACCTCAGCCTGGTCACAAAGAGTTACACTCAGATACATGAGCAC GGCAGCGTGCTCATAACTGTTTAACAACCAGCTGTCCTGGGAGGGGGACAGCTTTGTAAT GTTTGCCAATTTCCATGGTGTAAATGCTACCACCATGGCTGATTTCATCACTGCCAAGCA TAGACATCCCTAATAGGACACCACGGATCTGTCCCCGGCATCCGGCCCAGGGCCTGGCAC AAAGCATGCTCTAGGGAAATGCTTGCTGATTGAAAGGAAGGAAGAATGACTCTACAGTCA CACCTATGGCATCCCACAAAATCTGTCACATGGCTGCATAATCTCAGCCACTCTTTCACA ACTATAGACTCATACACGCGAAGTGCCAGATTCATGCACAACCACACAATCACATGGAAG TCACAGACGGCATCACAGACAGTCACAGCACTGTGTGTATGTTATAACACAAGCACACAA AACTCAGACAGCATCCCAGCTACACAGCCACTCCCAGAGGTGTCACCGTCACACTTGGTA ATTAATACTCATTACATTAGACACAGACAGACCAAGTTATAGTCAGACCTGGTTACACAC ATACACACACACAATATCACCATGACAAATACACATTACACACACACAACATCACAATGA CAAACACACATTACACACACAACATCACGATGACAAACACACATTACACACACAACATCA CGATGACAAACACACATTACACACACATCACAATGACAAACACAACATTACACACACACA ACATCACAATGACACACACATCACACACACATCACAATGACAAACACACAACATTACACA CATATACACACAGCCTGAGGGCCCTCCCCAGCCCAGACTAACACATCTCGGGGTGAGGAC CAGACCTTGTTCATAACCCTGGGCCTCTTAACCACTGATCTTTGAAATAAATGGCAAATA GTTGTACCTGGA OMIM ID 604520