Entrez gene ID | | 8797 |
Official gene symbol | | TNFRSF10A |
Full name | | tumor necrosis factor receptor superfamily, member 10a |
Aliases | | ,APO2,CD261,DR4,MGC9365,TRAILR-1,TRAILR1, |
Gene summary | | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq] |
Location | | Chromosome: 8 Locus: 8p21 |
Gene position | | 23082680 - 23048970 Map Viewer |
Gene orientation | | minus |
Gene size | | 33711 bp |
Gene sequence |
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OMIM ID | | 603611 |
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