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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TNFRSF10A (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID8797
Official gene symbolTNFRSF10A
Full nametumor necrosis factor receptor superfamily, member 10a
Aliases,APO2,CD261,DR4,MGC9365,TRAILR-1,TRAILR1,
Gene summaryThe protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq]
LocationChromosome: 8   Locus: 8p21
Gene position23082680 - 23048970  Map Viewer
Gene orientationminus
Gene size33711 bp
Gene sequence
OMIM ID603611