Entrez gene ID | | 8802 |
Official gene symbol | | SUCLG1 |
Full name | | succinate-CoA ligase, alpha subunit |
Aliases | | ,FLJ21114,FLJ43513,GALPHA,SUCLA1, |
Gene summary | | This gene encodes the alpha subunit of the heterodimeric enzyme succinate coenzyme A ligase. This enzyme is targeted to the mitochondria and catalyzes the conversion of succinyl CoA and ADP or GDP to succinate and ATP or GTP. Mutations in this gene are the cause of the metabolic disorder fatal infantile lactic acidosis and mitochondrial DNA depletion. [provided by RefSeq] |
Location | | Chromosome: 2 Locus: 2p11.2 |
Gene position | | 84686586 - 84650647 Map Viewer |
Gene orientation | | minus |
Gene size | | 35940 bp |
Gene sequence |
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OMIM ID | | 611224 |