Entrez gene ID | | 8817 |
Official gene symbol | | FGF18 |
Full name | | fibroblast growth factor 18 |
Aliases | | ,FGF-18,ZFGF5, |
Gene summary | | The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures. [provided by RefSeq] |
Location | | Chromosome: 5 Locus: 5q34 |
Gene position | | 170846667 - 170884630 Map Viewer |
Gene orientation | | plus |
Gene size | | 37964 bp |
Gene sequence |
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OMIM ID | | 603726 |
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