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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for DPM2 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 8818 Official gene symbol DPM2 Full name dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit Aliases ,FLJ80013,MGC111193,MGC21559, Gene summary Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. The protein encoded by this gene is a hydrophobic protein that contains 2 predicted transmembrane domains and a putative ER localization signal near the C terminus. This protein associates with DPM1 in vivo and is required for the ER localization and stable expression of DPM1 and also enhances the binding of dolichol-phosphate to DPM1. [provided by RefSeq] Location Chromosome: 9   Locus: 9q34.13 Gene position 130700763 - 130697374  Map Viewer Gene orientation minus Gene size 3390 bp Gene sequence >DPM2:complement(59861906..59865295):Length=3390 GTCCCGGTCCGAAACGTGTCTGGGCTGCTGCGAGAGACAGTCGGTGAAGGAAGGGAGGGG ACATCCGAAGGGTGGCCCGGGAGGCCGGGCGATGGTGAGGAGGGCGCCTCCTCTCCACCA AATCCTCCCCATCCATGCGGGCTAGGGACAGACCCTCCCCCGCCCACCCTAGGCTGGAAA GTGAACGTTCTCTGCACCTCTCCCACCTACAGACTAAGTAGGGCACCCGGTTTCCGTGTC GGCTTCACCACTGACTCGGAATGGGATCTACCTTTCTCTGAGCCTCACTTTTCCCATCTG AAAAATGGAACTTCCGATCCCGCACTCCCATCCCACTCTGGCCCCGGGACTCTGGGATAC TTAGAGATTGGCTTTTGGTGGGGCGGCGACAGGACTGTGGCCATGAAGGCCAGGGAGTCT GGGTCCCCAACTCGGTCCCATTCCCTAGAGAGATTCGGGCAGCAACCGGCCCCACAATGC TCTTGAGAACTACACTTCGCCGATATGCAAAGAAGAGGAGGCGGTTCCTGCTCGTCTCCG ACGAGGTGGGCCCGAGCAGGCCTGGGGACTACGACTCCCGGCGTGCTCCGCAGTCCAAAG CCGGAAGAGCGTGGACCCGGAACCGGATGTGGCTTGCGGCTCGGGTGGCTGAGCGCGCGG GGAAATGGTGAGATTGGCACCGTGTGCCGGAGATAGGGGCGTCTGGGGGTGGGGTCCCGG GTCTGCTCAGGAGCTGGGGCATGGGCACTTGGAACGGGGATTGCTCTCCCGCCCCCACTA TTGTACGGACGACAACGCGGAGGCCTAGCATTCTCTCCCAGCCTAGAAACTGATCCCTAG TCAGCCCTCTACCATCTGTTGAATGGGAAGCTTAGACCGTGATCGGGCCGCGACGCCCCG CTTCCATTAGTGCGCCGAAATAGAGGGTCACTTCGTCAGCTGAGACCTCCCTTTTCTCCA GGCCACGGGGACAGACCAGGTGGTGGGACTCGGCCTCGTCGCCGTTAGCCTGATCATCTT CACCTACTACACCGCCTGGGTGATTCTCTTGGTATGTCATTCTCCCCGTCCGCTGCTCAC CTTCCCCGAGCCCTGGCACCGCCAGAGCAACTACTATATAGGCTCTAGGCACGGCGCTGG CTTCATTGCCTGCCTCATCTCTTGAACTCTCCAGAACAACTCTATGAGGAAGATGCCAGT GGTACCGCATTTTATAGATGAGATAGCTGAGGCTAGGGGAGAAGGATCTGGCCCAAGATT GCATCCTTAGCCGCTACACTTATAACTCTGTTTCCGGCTTGCTTTGACTTTTGGGGGAGT TCTGTTCCTTCTGGGTTAGCCTGCTGACTCTTAGGCATGGCAAACGCCAGTGATATTTGT GAAGGCCTTTAGGATATTTTTTTCTTGTGGGAAAACTTGTTGGTTATTGCTTAAGAAGTG CAGTGTGTCTGGAAGTGCAGAACTTGGTATCCTTTAGAGAAAAAATATTAGTGAAGAAGC CCTGGAGGCCCAGGTTGGGAGTCAGTCGAGGATTCCTCAAGTACCATTTGCTAGGCTGTG AGGTGCCTTAGGGCAGGTCTCTTGTGCCCTGTTCTCTTGTCCCCACCACCAACCTATAGC AGGCACCAAAGCAAGTGCCCGGTAAATACCAATAAGAAATTAAGGAAAGAAACAAACCAC GACACCCAAATGCCGTAATCTTAAAGAAAAGCAAATGCAGTCCCAGTCCTCTGAATGGGT CAGCCCCTTAGATGGAGGAGGTGGGACGTTTGGGCTTGGGGGCTCGGCAAGGCAAGCAAG ACACACCAGAGCTCTTCCCTCGATGCCAGCCATTCATCGACAGTCAGCATGTCATCCACA AGTATTTCCTGCCCCGAGCCTATGCTGTCGCCATCCCACTGGCTGCAGGCCTCCTGCTGC TCCTGTTTGTGGGTAAGTCATCACCTCCTCCCCTTGACCCTGGGCAGGGTTTCGGGAAGA CCCCACCTCTGAACATGCTTCCACACTTTGGCGGTGCTGGAAGCTGCTTGCCCCGAACTC ACCCGTGGGGTTTTCCTGTTCATCCTTCGAGGCTGCCAGTCAGTAACCTCTGGGTTTCCT GGTGCCCCAGGCTTTTTGGACTCCAATGACCTGTCTACCTCTTTCCTGCCCCAACCCCAT CATCACTCTGCTCACACCTCAGTCACCCTCTTGTCACCCTGGCTTCTAATTCCTGCACCT CTCTCTCTCATGGCTTCCTAGGGATGGGGACTGTGTCTCCATCATTACTGCACATCTAGA ACAGGCTGTGGCACTGAGGCTGTGCTCAGAAAGTCATTTGGATGAGTCAGTCAACAGCCG GGTGCCTGGATGATGGGTGGATGGATGGGTGGGTGGGTGAGGTGTAGGAGGAGGTGGGTA GGTATGTAGGTGGACAGACAAGTGGTTGACCGGGTGATCGATAGATGGGTGGATCTTGTT CCCCTTGGAATCTGAAACACTAAATGCAGCATCTTGCTTGAGGCAGGCACTCAGTTGGTG TTTGTTGAGTGAATGTGAGTAGACATATGCCTTGACGAATGACTAGGGAGATAAGCAGGT TCCCTGGAGGATGGTTGGGTAGGTTCACAGCCCTGTGTGTGGGTGGCTCTGCTGTGTCAT GCCCTGGCCTCCCAGCAGCCCTGAGCTTAGATCTTATGTGGCCTTTCTGGTCTGTGTATC CCAGGACTGTTCATCTCCTATGTGATGCTGAAGACCAAGAGAGTGACCAAGAAGGCTCAG TGAAGGTCCCGCAGGGATGAGGCTGCCAGCCCCTTCTCTGCTTCCCCTCCAGCACAGGGA CCAAGTGGGGGAGCCTGCAGAACCTGTCCAGGCACAGTGGCTCCTCAAGCCTGCCTGTCC TGCAGAGTCCCCATGGCATGGAGCTTACACCTGACTGACTGGAGCCCCCTCCCCGACTCC CACTTCCAGAAGCTAGGAGGGAGGGATACCTGGAAGACTCCGGTCACCTCCTTCTTGCTC AGGGCCTAAAAGATGCTGGTCCTCCCAACCTCACTCTCAGACTCCCTGCCACCTTTTCCC CTGGGTTCTGCCGTCTTGCCTCACTTCCCCTCCTGTCACATGCTGACGTTGGACTTAGCA GGTTCTAAGGCCACATGTGTGACCTCTCTGACTTCTCTTCCTCCACCAAGGCAGCTTTCC TTACCCTGACACAGCCCCAGACCCCACAAAGCCTTCTGGACCTGGAAAGCCTGGGGAAGG ACTGACAGACCCCAGGACCAGCCCTGGGGCTCAGGGCAGCCACCCCGGGCCGCTGACCGA CTGACCTCTCCTCACGGAGGCCCAGCCCCAAAGCCCCAGGGCTGGCCCGTTTGGGACAGC TGACCAATAAACACTGATGGTGTGTTTGTC OMIM ID 603564