Entrez gene ID | | 8824 |
Official gene symbol | | CES2 |
Full name | | carboxylesterase 2 (intestine, liver) |
Aliases | | ,CE-2,CES2A1,PCE-2,iCE, |
Gene summary | | This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance. Alternatively spliced transcript variants have been found for this gene. |
Location | | Chromosome: 16 Locus: 16q22.1 |
Gene position | | 66968347 - 66978999 Map Viewer |
Gene orientation | | plus |
Gene size | | 10653 bp |
Gene sequence |
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OMIM ID | | 605278 |
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