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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for VNN2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID8875
Official gene symbolVNN2
Full namevanin 2
Aliases,FOAP-4,GPI-80,
Gene summaryThis gene product is a member of the Vanin family of proteins which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. The encoded protein is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. This gene lies in close proximity to, and in same transcriptional orientation as two other vanin genes on chromosome 6q23-q24. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]
LocationChromosome: 6   Locus: 6q23-q24
Gene position133084598 - 133065009  Map Viewer
Gene orientationminus
Gene size19590 bp
Gene sequence
OMIM ID603571