Entrez gene ID | | 8891 |
Official gene symbol | | EIF2B3 |
Full name | | eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa |
Aliases | | ,EIF-2B,EIF2Bgamma, |
Gene summary | | The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1p34.1 |
Gene position | | 45452361 - 45316194 Map Viewer |
Gene orientation | | minus |
Gene size | | 136168 bp |
Gene sequence |
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OMIM ID | | 606273 |
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